产品货号：
Z27581
中文名称：
SR-BI/SCARB1抗体
英文名称：
Anti-SR-BI/SCARB1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SR-BI/SCARB1 Antibody |
| 指标别名 | CD36 and LIMPII analogous 1;CD36 antigen like 1;CD36L1;CLA 1;CLA1;SCARB1;SRB1;SR-B1;SR-BI |
| 克隆性 | Polyclonal |
| 检验物种 | mouse,rat |
| 应用范围 | WB,IHC,ICC,FCM |
| 基因名称 | SCARB1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of mouse SCARB1 (478-509aa KKGSQDKEAIQAYSESLMSPAAKGTVLQEAKL),different from the related rat sequence by one amino acid. |
| 实际分子量 | 85KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Scavenger receptor class B member 1 (SRB1),also known as SR-BI,is a protein that in humans is encoded by the SCARB1 gene.SR-BI functions as a receptor for high-density lipoprotein.Scavenger receptor class B,type I (SR-BI) is an integral membrane protein found in numerous cell types/tissues,including the liver and adrenal.It is best known for its role in facilitating the uptake of cholesteryl esters from high-density lipoproteins in the liver.This process drives the movement of cholesterol from peripheral tissues towards the liver for excretion.This movement of cholesterol is known as reverse cholesterol transport and is a protective mechanism against the development of atherosclerosis,which is the principal cause of heart disease and stroke.SR-BI has also been identified in the livers of non-mammalian species (turtle,goldfish,shark,chicken,frog,and skate),suggesting it emerged early in vertebrate evolutionary history.The turtle also seems to upregulate SB-RI during egg development,indicating that cholesterol efflux may be at peak levels during developmental stages. |
| Uniprot ID | Q61009 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | scavenger receptor class B,member 1 |
| 蛋白名全称 | Scavenger receptor class B member 1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 22 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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